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PLINEST (Polynucleotides)

Introducing PLINEST – a quick and effective rejuvenation treatment for skin, eyes and hair. Help to remodel areas with a high fibrous content such as acne scars, fine lines and hair density.

Looking to prevent skin damage and maintaining younger patient’s skin quality? Then this is the perfect starter treatment for you.

It helps to remodel areas with a high fibrous content such as acne scars.

Polynucleotides with High Purification Technology (PN-HPTTM) are natural origin products obtained through a technology featuring a high degree of purification and safety.

PN-HPTTM are deoxyribonucleotide polymers (DNA fractions)
with a crucial role in:
• Skin quality
• Restoring radiance and freshness
• Promoting bio-regeneration
• Reducing wrinkles and skin laxity
The polynucleotide-HPTTM PRIMING process prepares the skin
and makes it more receptive to medical, aesthetic, and anti-ageing
treatments. It generates a synergistic effect with: laser,
radiofrequency, fillers, peeling, needling, and surgery.

How it works?

Patients: 143 of both sexes; in 91 patients only one skin area was treated, in 37 patients two skin areas were treated simultaneously and in the other cases (15 patients) more than two skin areas were treated simultaneously.

Prevention treatment for younger skin: 3 intradermal treatments – one every 3 weeks – followed by a maintenance treatment every 2-3 months.

Recovery treatment for ageing skin: 4 infiltrations treatment, one every 1-2 weeks, followed by maintenance sessions every 1-3 months.

Lumiere Skin Clinic | Manchester Lumiere Skin Clinic | Manchester

Frequently Asked Questions

  1. How safe is this procedure?

    Safety: The product was very well tolerated and the injections without much pain. No cases of severe side effects due to the highly bio-compatible nature of the gel/product.

  2. How efficient is this procedure?

    Efficacy: 91% of patients demonstrated clinical improvement in the reduction of superficial fine lines and wrinkles based on physician assessment.
    +14.7% improvement in skin hydration vs baseline.
    +21.8% increase in skin elasticity.

  3. How to patients respond to this procedure?

    In more than 90% of the subjects PN-HPTTM demonstrated overall clinical improvements of the skin texture and reductions of superficial fine wrinkles.

  4. What are the treatment protocols and injection techniques: for younger skin for bio-regeneration?

    2ml intradermally with micro-droplet or linear retrograde technique.
    One session (2ml) every 14 or 21 days for a total of 3 sessions.

  5. What are the treatment protocols and injection techniques: acne scar improvement?

    30 Micro-droplets (0.1-0.2ml at each injection point) subdermally.
    One session (4ml) every 3 weeks for total of 2 sessions.

  6. Areas of treatment?

    Face, Neck, and Décolleté.

  7. Depth of injection?


*Individual results may vary.

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